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US 281 South Shut Down After Multi-Vehicle Collision

SAN ANTONIO, TX - February 22nd, 2026 - A significant multi-vehicle collision has brought southbound US 281 to a standstill near San Pedro Avenue this Sunday afternoon, creating a ripple effect of traffic congestion across a large portion of San Antonio. The incident, first reported around 1:30 p.m. CST, involved an undetermined number of vehicles and has prompted a full response from San Antonio Police Department (SAPD) and emergency medical services.

Initial reports indicate the crash occurred in the southbound lanes of US 281, just north of the San Pedro Avenue exit. While the precise sequence of events leading to the collision remains under investigation, preliminary assessments suggest a combination of factors may have contributed, including heavy Sunday afternoon traffic and potentially adverse weather conditions. Although the weather is currently clear, earlier showers left roads slick in certain areas.

SAPD officers are on scene directing traffic, attempting to reroute vehicles away from the impacted area. However, the complete closure of southbound lanes is causing substantial delays, stretching back several miles. The northbound lanes are also experiencing slowdowns due to rubbernecking and the need to manage emergency vehicle access. Transportation officials are strongly advising motorists to avoid US 281 South altogether and seek alternative routes.

"This is a major artery for San Antonio traffic, especially on weekends," stated Officer Maria Hernandez, a spokesperson for SAPD, during a brief on-scene update. "We are working diligently to clear the wreckage and ensure the safety of everyone involved. However, this will be a prolonged operation. We urge drivers to be patient and plan accordingly."

News 4 San Antonio's crew on the scene has captured images of a significant amount of damage to multiple vehicles, suggesting a high-impact collision. While the extent of injuries is currently unknown, paramedics were observed transporting at least three individuals to local hospitals. The severity of their injuries has not been released at this time. Officials have confirmed that multiple ambulances and fire crews responded to the incident, indicating the potential for numerous casualties.

This incident highlights growing concerns about traffic safety on US 281, a major thoroughfare that has seen an increase in collisions in recent years. Local advocacy groups have been lobbying for improved infrastructure, including expanded highway lanes and enhanced traffic management systems. A recent study by the Texas Department of Transportation (TxDOT) identified US 281 as a high-risk corridor due to its high traffic volume and the increasing number of distracted drivers. The study proposed several solutions, including the implementation of intelligent traffic systems and increased law enforcement presence, but funding for these projects remains a challenge. [ Link to TxDOT Study on US 281 ].

Furthermore, the rapid population growth in San Antonio has placed increased strain on the city's infrastructure. The expanding suburbs and the influx of new residents have led to more vehicles on the road, exacerbating existing traffic congestion and increasing the likelihood of accidents. City planners are currently working on a comprehensive transportation plan aimed at addressing these challenges, but the implementation of these long-term solutions will take years.

Motorists are encouraged to check real-time traffic conditions using apps like Google Maps or Waze before embarking on their journeys. Alternate routes currently being suggested by transportation authorities include Interstate 10 West and Blanco Road. Residents in the vicinity of the crash are also advised to expect increased emergency vehicle traffic and potential delays. News 4 San Antonio will continue to provide live updates on this developing story throughout the afternoon and evening. We will bring you the latest information on the cause of the crash, the extent of the injuries, and the estimated time for reopening US 281 South.


Read the Full news4sanantonio Article at:
[ https://news4sanantonio.com/news/instagram/major-crash-shuts-down-southbound-us-281-at-san-pedro-avenue ]